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Article

Strong protective effect of DR3 against ulcerative colitis in the Spanish population.

The American journal of gastroenterology - 1 Dec 2007

Gómez-García María, Oliver Javier, Márquez Ana, Mendoza Juan L, López-Nevot Miguel Angel, Fernández-Arquero Miguel, González-Escribano María F, Díaz-Rubio Manuel, de la Concha Emilio G, Urcelay Elena, Martín Javier, Martínez Alfonso

Abstract excerpt

OBJECTIVES: Ulcerative colitis (UC) is a chronic inflammatory disease affecting the colon. Major histocompatibility complex (MHC) on the short arm of human chromosome 6 has been thoroughly studied as a susceptibility locus. However, one of the strongest MHC associations found, that of HLA-DR3 with UC protection, has not been observed in all populations. Our aim in the present study was to evaluate this negative...

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Identifiers

PMID: 17714554
DOI: 10.1111/j.1572-0241.2007.01487.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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