Article
FcRL3 gene promoter variant is associated with peripheral arthritis in Crohn's disease.
Inflammatory bowel diseases - 1 Sept 2009
Mendoza Juan L, Lana Raquel, Martin Maria C, de la Concha Emilio G, Urcelay Elena, Diaz-Rubio Manuel, Abreu Maria T, Mitchell Adele A
Abstract excerpt
BACKGROUND: The mechanisms responsible for the pathogenesis of peripheral arthropathies (PA) in Crohn's disease (CD) are largely unknown, although many studies indicate that genetic and environmental factors are likely to contribute to risk. METHODS: Because variants in the Fc receptor-like 3 (FcRL3) gene have recently been associated with rheumatoid arthritis and several other autoimmune diseases, we tested 2...
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