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Article

Polymorphisms in the promoter region of tumor necrosis factor alpha (TNF-alpha) and the HLA-DRB1 locus in Mexican mestizo patients with ulcerative colitis.

Immunology letters - 15 Aug 2004

Yamamoto-Furusho Jesús K, Uscanga Luis F, Vargas-Alarcón Gilberto, Rodríguez-Pérez José M, Zuñiga Joaquin, Granados Julio

Abstract excerpt

Tumor necrosis factor alpha (TNF-alpha) gene is located within the class III region of the major histocompatibility complex (MHC) on the short arm of the human sixth chromosome. Two polymorphisms in the promoter region of the TNF-alpha gene (-308 and -238) have been associated with the genetic su...

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Source

Identifiers

PMID: 15325795
DOI: 10.1016/j.imlet.2004.05.015

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15325795-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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