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Article

Spatiotemporal dynamics of intracellular calcium in the mouse egg injected with a spermatozoon

1 Dec 1997

Abstract excerpt

Oscillatory rises in intracellular Ca2+ concentration ([Ca2+]i) are the pivotal signal in the fertilization of mammalian eggs. The spatiotemporal dynamics of [Ca2+]i rises in mouse eggs subjected to intracytoplasmic sperm injection (ICSI) were analysed by Ca2+ imaging and compared with those subjected to in-vitro fertilization (IVF). The first Ca2+ transient occurred 15-30 min after ICSI in most eggs, and was...

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PMID: 9464853
DOI: 10.1093/molehr/3.12.1087

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