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Article

Fertilization and early embryology: The role of calcium in mammalian oocyte maturation and egg activation

1 Aug 1993

Abstract excerpt

The maturation of the immature oocyte and the fertilization of a mature egg are two absolute prerequisites for mammalian embryo development. There is increasing evidence in mammals that both oocyte maturation and egg activation at fertilization are controlled by changes in intracellular free Ca2+ levels. The role of Ca2+ changes at fertilization is clear in that they are both required and sufficient for egg...

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PMID: 8408526
DOI: 10.1093/oxfordjournals.humrep.a138240

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