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Article

The inhibition of endocytosis affects HDL-lipid uptake mediated by the human scavenger receptor class B type I.

Molecular membrane biology - 1 Jan 2000

Zhang Yi, Ahmed Ayesha M, Tran Thu L, Lin Judy, McFarlane Nicole, Boreham Douglas R, Igdoura Suleiman A, Truant Ray, Trigatti Bernardo L

Abstract excerpt

The scavenger receptor SR-BI plays an important role in the hepatic clearance of HDL cholesterol and other lipids, driving reverse cholesterol transport and contributing to protection against atherosclerosis in mouse models. We characterized the role of endocytosis in lipid uptake from HDL, mediated by the human SR-BI, using a variety of approaches to inhibit endocytosis, including hypertonic shock, potassium or...

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Identifiers

PMID: 17710648
DOI: 10.1080/09687680701300410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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