Article
Deficiency of calcium and magnesium induces apoptosis via scavenger receptor BI.
Life sciences - 28 Mar 2011
Feng Hong, Guo Ling, Gao Haiqing, Li Xiang-An
Abstract excerpt
AIMS: Cells undergo apoptosis in stressed status such as in intracellular calcium overload or extracellular calcium/magnesium deficiency. The mechanisms of how deficiency of the divalent metal ions induces apoptosis remain to be defined. Scavenger receptor BI (SR-BI) is a high density lipoprotein (HDL) receptor. Recent studies demonstrated that SR-BI is a stress response molecule which induces apoptosis upon...
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