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Article

Tryptophan 415 Is Critical for the Cholesterol Transport Functions of Scavenger Receptor BI.

Biochemistry - 12 Jan 2016

Holme Rebecca L, Miller James J, Nicholson Kay, Sahoo Daisy

Abstract excerpt

High density lipoproteins (HDL) are anti-atherogenic particles, primarily due to their role in the reverse cholesterol transport pathway whereby HDL delivers cholesteryl esters (CE) to the liver for excretion upon interaction with its receptor, scavenger receptor BI (SR-BI). We designed experiments to test the hypothesis that one or more of the eight highly conserved tryptophan (Trp; W) residues in SR-BI are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26652912
DOI: 10.1021/acs.biochem.5b00804
PMCID: PMC5428993

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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