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Article

Cost minimization of ribosomal frameshifts.

Journal of theoretical biology - 7 Nov 2007

Seligmann Hervé

Abstract excerpt

Properties of mRNA leading regions that modulate protein synthesis are little known (besides effects of their secondary structure). Here I explore how coding properties of leading regions may account for their disparate efficiencies. Trinucleotides that form off frame stop codons decrease costs of ribosomal slippages during protein synthesis: protein activity (as a proxy of gene expression, and as measured in...

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Identifiers

PMID: 17706680
DOI: 10.1016/j.jtbi.2007.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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