Article
Genetic Susceptibility to Life-threatening Respiratory Syncytial Virus Infection in Previously Healthy Infants.
The Pediatric infectious disease journal - 1 Nov 2020
López Eduardo Luis, Ferolla Fausto Martin, Toledano Analía, Yfran Eduardo Walter, Giordano Ana Clara, Carrizo Bárbara, Feldman Florencia, Talarico Laura Beatriz, Caratozzolo Ana, Contrini María Marta, Acosta Patricio Leandro
Abstract excerpt
BACKGROUND: Genetic background may be an important host determinant of respiratory syncytial virus (RSV) disease severity, but full characterization of susceptibility genes remains unclear. This study aimed to assess the presence of specific single-nucleotide polymorphisms (SNPs) in selected genes codifying for different components of the antiviral innate immune response, to determine their role for developing...
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