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Article

Human Genetic Factors and Respiratory Syncytial Virus Disease Severity

1 Oct 2008

Abstract excerpt

SUMMARY: To explain the wide spectrum of disease severity caused by respiratory syncytial virus (RSV) and because of the limitations of animal models to fully parallel human RSV disease, study of genetic influences on human RSV disease severity has begun. Candidate gene approaches have demonstrated associations of severe RSV in healthy infants with genetic polymorphisms that may alter the innate ability of humans...

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PMID: 18854487
DOI: 10.1128/cmr.00017-08

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