Article
Detection of near-atmospheric concentrations of CO2 by an olfactory subsystem in the mouse.
Science (New York, N.Y.) - 17 Aug 2007
Hu Ji, Zhong Chun, Ding Cheng, Chi Qiuyi, Walz Andreas, Mombaerts Peter, Matsunami Hiroaki, Luo Minmin
Abstract excerpt
Carbon dioxide (CO2) is an important environmental cue for many organisms but is odorless to humans. It remains unclear whether the mammalian olfactory system can detect CO2 at concentrations around the average atmospheric level (0.038%). We demonstrated the expression of carbonic anhydrase type II (CAII), an enzyme that catabolizes CO2, in a subset of mouse olfactory neurons that express guanylyl cyclase D...
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