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Article

Hybrid neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems.

Science (New York, N.Y.) - 29 Feb 2008

Cayirlioglu Pelin, Kadow Ilona Grunwald, Zhan Xiaoli, Okamura Katsutomo, Suh Greg S B, Gunning Dorian, Lai Eric C, Zipursky S Lawrence

Abstract excerpt

Carbon dioxide (CO2) elicits different olfactory behaviors across species. In Drosophila, neurons that detect CO2 are located in the antenna, form connections in a ventral glomerulus in the antennal lobe, and mediate avoidance. By contrast, in the mosquito these neurons are in the maxillary palps (MPs), connect to medial sites, and promote attraction. We found in Drosophila that loss of a microRNA, miR-279, leads...

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Identifiers

PMID: 18309086
DOI: 10.1126/science.1149483
PMCID: PMC2714168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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