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Elevated CO2 regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans

3 Dec 2019

Abstract excerpt

Abstract Carbon dioxide (CO 2 ) is sensed by cells and can trigger signals to modify gene expression in different tissues leading to changes in organismal functions. Despite accumulating evidence that several pathways in various organisms are responsive to CO 2 elevation (hypercapnia), it has yet to be elucidated how hypercapnia activates genes and signaling pathways, or whether they interact, are integrated, or...

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PMID: 31796806
DOI: 10.1038/s41598-019-54683-0

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