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Article

A Sensor for Low Environmental Oxygen in the Mouse Main Olfactory Epithelium.

Neuron - 21 Dec 2016

Bleymehl Katherin, Pérez-Gómez Anabel, Omura Masayo, Moreno-Pérez Ana, Macías David, Bai Zhaodai, Johnson Randall S, Leinders-Zufall Trese, Zufall Frank, Mombaerts Peter

Abstract excerpt

Sensing the level of oxygen in the external and internal environments is essential for survival. Organisms have evolved multiple mechanisms to sense oxygen. No function in oxygen sensing has been attributed to any mammalian olfactory system. Here, we demonstrate that low environmental oxygen directly activates a subpopulation of sensory neurons in the mouse main olfactory epithelium. These neurons express the...

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Identifiers

PMID: 27916458
DOI: 10.1016/j.neuron.2016.11.001
PMCID: PMC5196021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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