Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.

Abstract excerpt

Variation in human taste is a well-known phenomenon. However, little is known about the molecular basis for it. Bitter taste in humans is believed to be mediated by a family of 25 G protein-coupled receptors (hT2Rs, or TAS2Rs). Despite recent progress in the functional expression of hT2Rs in vitro, up until now, hT2R38, a receptor for phenylthiocarbamide (PTC), was the only gene directly linked to variations in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Phenylthiourea
• Share to Polymorphism, Single Nucleotide