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Article

CTCF mediates insulator function at the <i>CFTR</i> locus

14 Nov 2007

Abstract excerpt

Regulatory elements that lie outside the basal promoter of a gene may be revealed by local changes in chromatin structure and histone modifications. The promoter of the CFTR (cystic fibrosis transmembrane conductance regulator) gene is not responsible for its complex pattern of expression. To identify important regulatory elements for CFTR we have previously mapped DHS (DNase I-hypersensitive sites) across 400 kb...

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Share to Cystic Fibrosis Research Advances
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PMID: 17696881
DOI: 10.1042/bj20070429

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