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Article

Differential gene expression in melanocytic nevi with the V600E BRAF mutation.

Genes, chromosomes & cancer - 1 Nov 2007

Bloethner Sandra, Snellman Erna, Bermejo Justo Lorenzo, Hiripi Eva, Gast Andreas, Thirumaran Ranjit K, Wellenreuther Ruth, Hemminki Kari, Kumar Rajiv

Abstract excerpt

We studied gene expression in 18 melanocytic nevi with and four nevi without the V600E mutation in the BRAF gene using HG-U133A 2.0 microarray with 22,277 transcripts. Data analysis revealed 92 genes up-regulated and 105 genes down-regulated in nevi with the mutation compared to nevi without mutation. Pathway analysis showed that differentially regulated genes mapped to 10 genetic networks. The major network...

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PMID: 17696195
DOI: 10.1002/gcc.20488

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BRAF
MITF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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