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Article

The microRNA molecular signature of atypic and common acquired melanocytic nevi: differential expression of miR-125b and let-7c

17 Dec 2010

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNAs, which regulate gene expression through base pairing with mRNA and which are crucially involved in carcinogenesis (the so-called oncomiRs). We compared the miRNA signature between acquired melanocytic nevi showing clinical atypia (atypic nevi, AN) and common acquired nevi (common nevi, CN). We obtained miRNA profiles from 41 biopsies (22 AN and 19 CN) and showed that...

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PMID: 21166724
DOI: 10.1111/j.1600-0625.2010.01163.x

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