Article
Frequent nuclear expression of beta-catenin protein but rare beta-catenin mutation in pulmonary sclerosing haemangioma.
Journal of clinical pathology - 1 Mar 2008
Chiang P-M, Yuan R-H, Hsu H-C, Mao T-L, Hu R-H, Lai P-L, Jeng Y-M
Abstract excerpt
BACKGROUND: Pulmonary sclerosing haemangioma (PSH) is an uncommon tumour that is composed of glandular/papillary lining cells and polygonal cells. The biological behaviour of this tumour has been investigated; however, the molecular pathogenesis of PSH remains unknown. AIMS: To characterise the role of the Wnt/beta-catenin pathway in the genesis of PSH. METHODS: 37 PSH samples were investigated...
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