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Article

Frequent mutation and nuclear localization of β-catenin in sertoli cell tumors of the testis.

The American journal of surgical pathology - 1 Jan 2014

Perrone Federica, Bertolotti Alessia, Montemurro Gabriella, Paolini Biagio, Pierotti Marco A, Colecchia Maurizio

Abstract excerpt

The Sertoli cell tumor (SCT) of the testis is a sex cord stromal tumor, usually sporadic, rarely associated with genetic syndromes. Much remains unclear about the molecular genetic changes involved in SCT and its histogenesis. Recently, nuclear β-catenin immunostaining has been reported in a case of bilateral SCT, but the molecular basis of the aberrant nuclear β-catenin expression remains uncertain. In the...

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Source

Identifiers

PMID: 24061522
DOI: 10.1097/PAS.0b013e31829cdbc6

Genes

SCT
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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