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Article

β-catenin (CTNNB1) mutation and LEF1 expression in sinonasal glomangiopericytoma (sinonasal-type hemangiopericytoma).

Virchows Archiv : an international journal of pathology - 1 Aug 2018

Suzuki Yuka, Ichihara Shu, Kawasaki Tomonori, Yanai Hiroyuki, Kitagawa Satoshi, Shimoyama Yoshie, Nakamura Shigeo, Nakaguro Masato

Abstract excerpt

Sinonasal glomangiopericytoma (SN-GPC) is an uncommon mesenchymal tumor with myoid differentiation. Recently, mutations in exon 3 of the gene coding for β-catenin (CTNNB1) and its nuclear expression were discovered in SN-GPC. β-catenin protein is a key regulatory molecule of the canonical Wnt signaling pathway. The expression of β-catenin target proteins is not well characterized in SN-GPC. We examined three...

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Source

Identifiers

PMID: 29736797
DOI: 10.1007/s00428-018-2370-9

Genes

CTNNB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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