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Article

β-catenin/Wnt signalling pathway in fibromatosis, metaplastic carcinomas and phyllodes tumours of the breast.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Nov 2010

Lacroix-Triki Magali, Geyer Felipe C, Lambros Maryou B, Savage Kay, Ellis Ian O, Lee Andrew H S, Reis-Filho Jorge S

Abstract excerpt

Wnt signalling pathway is known to have a critical role in carcinogenesis and in epithelial-to-mesenchymal transition. Upon Wnt activation, β-catenin is translocated from the membrane to the cytoplasm and nucleus, where it interacts with transcriptional activators. It has been suggested that various spindle cell lesions of the breast may harbour Wnt pathway activation. Given that β-catenin nuclear localization...

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Source

Identifiers

PMID: 20693983
DOI: 10.1038/modpathol.2010.141

Genes

CTNNB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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