Article
Detection of mutant p53 protein in workers occupationally exposed to benzidine.
Journal of occupational health - 1 Jul 2007
Xiang Cui-Qin, Shen Chun-Lin, Wu Zi-Rong, Qin Yi-Qiu, Zhang Yun-Ying, Liu Cha-Zhen, Chen Ji-Gang, Zhang Sheng-Nian
Abstract excerpt
To investigate the expression of mutant p53 protein in workers occupationally exposed to benzidine, we detected mutant p53 protein by immuno-PCR assay in the serum of 331 benzidine-exposed healthy workers, while we classified exfoliated urothelial cells in urine samples with Papanicoloau's grading (PG). The Papanicoloau's grading classified exfoliated urothelial cells of the subjects from grade I (normal cells)...
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