Article
Tobacco smoking, occupation, and p53 nuclear overexpression in early stage bladder cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2000
Zhang Z F, Sarkis A S, Cordon-Cardo C, Dalbagni G, Melamed J, Aprikian A, Pollack D, Sheinfeld J, Herr H W, Fair W R
Abstract excerpt
Epidemiological studies show an increased risk of bladder cancer associated with tobacco smoking and occupational exposures. Certain carcinogens in tobacco and occupational exposures cause DNA damage and may produce specific mutations. TP53 is considered a common target for carcinogenic agents, a...
Topics
- Aged
- Carcinoma, Transitional Cell
- Chemical Industry
- Coloring Agents
- Cooking
- Female
- Humans
- Male
- Middle Aged
- Neoplasm Staging
- Occupational Exposure
- Odds Ratio
- Phenotype
- Risk Factors
- Smoking