GSTP1 A1578G (Ile105Val) polymorphism in benzidine-exposed workers: an association with cytological grading of exfoliated urothelial cells.

doi:10.1097/00008571-200307000-00006

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GSTP1 A1578G (Ile105Val) polymorphism in benzidine-exposed workers: an association with cytological grading of exfoliated urothelial cells.

Pharmacogenetics - 1 Jul 2003

Ma Qingwen, Lin Guofang, Qin Yiqiu, Lu Daru, Golka Klaus, Geller Frank, Chen Jigang, Shen Jianhua

Abstract excerpt

A polymorphism at codon 105 (Ile/Val) in the GSTP1 gene has been associated with a higher risk for different cancer types. To assess the role of GSTP1 polymorphisms in the development of benzidine-related bladder cancer, GSTP1 AA, AG and GG genotypes were determined in occupationally benzidine-exposed Chinese workers without known disease and benzidine-exposed bladder cancer patients from the same cohort of the...

Topics

Aged
Alleles
Asian People
Benzidines
Carcinogens
Case-Control Studies
China
Cohort Studies
Female
Gene Frequency
Glutathione Transferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Middle Aged

Occupational Exposure

Odds Ratio

Polymorphism, Genetic

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 12835616
DOI: 10.1097/00008571-200307000-00006

Genes

GSTP1

Variants

Provenance

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