Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ITGA4 polymorphisms and susceptibility to multiple sclerosis.

Journal of neuroimmunology - 1 Sept 2007

O'Doherty Catherine, Roos Izaura M, Antiguedad Alfredo, Aransay Ana M, Hillert Jan, Vandenbroeck Koen

Abstract excerpt

In multiple sclerosis (MS), alpha(4)beta(1) integrin, also known as Very Late Antigen 4 (VLA4), facilitates migration of leukocytes across the blood brain barrier. Several studies suggest that expression of alpha(4) integrin may be increased in MS patients compared to controls, and down-regulatio...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Genetic Predisposition to Disease
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multiple Sclerosis

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Share to White People

Source

Identifiers

PMID: 17689671
DOI: 10.1016/j.jneuroim.2007.07.006

Genes

ITGA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17689671-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ITGA4 polymorphisms and susceptibility to multiple sclerosis.PMID 17689671Read ↗

VLA4 Gene Polymorphism and Susceptibility to Multiple Sclerosis in Slovaks.Semantic proximity Read ↗

The role of VLA4 polymorphisms in multiple sclerosis: an association study.Semantic proximity Read ↗

A Novel Association of Polymorphism in the ITGA4 Gene Encoding the VLA-4 α4 Subunit with Increased Risk of Alzheimer's Disease.Semantic proximity Read ↗

Polymorphisms in the interleukin-4 and IL-4 receptor genes and multiple sclerosis: a study in Spanish-Basque, Northern Irish and Belgian populations.Semantic proximity Read ↗

The CTLA-4 gene is associated with multiple sclerosis.Semantic proximity Read ↗

CTLA4 is associated with susceptibility to multiple sclerosis.Semantic proximity Read ↗

The Systemic Lupus Erythematosus-Associated Single Nucleotide Polymorphism rs1143678 in Integrin αM Cytoplasmic Tail Generates a 14-3-3ζ Binding Site That Is Proinflammatory.Semantic proximity Read ↗

CTLA4 dimorphisms and the multiple sclerosis phenotype.Semantic proximity Read ↗

CTLA-4 gene and the susceptibility of multiple sclerosis: an updated meta-analysis study including 12,916 cases and 15,455 controls.Semantic proximity Read ↗

Role of interleukin 4 in Spanish multiple sclerosis patients.Semantic proximity Read ↗

Interleukin 7 receptor alpha polymorphism rs6897932 and susceptibility to multiple sclerosis in the Western Balkans.Semantic proximity Read ↗

The CD11b-integrin (ITGAM) and systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.