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Article

Is gray matter volume an intermediate phenotype for schizophrenia? A voxel-based morphometry study of patients with schizophrenia and their healthy siblings.

Biological psychiatry - 1 Mar 2008

Honea Robyn A, Meyer-Lindenberg Andreas, Hobbs Katherine B, Pezawas Lukas, Mattay Venkata S, Egan Michael F, Verchinski Beth, Passingham Richard E, Weinberger Daniel R, Callicott Joseph H

Abstract excerpt

BACKGROUND: Shared neuropathological characteristics of patients with schizophrenia and their siblings might represent intermediate phenotypes that could be used to investigate genetic susceptibility to the illness. We sought to discover previously unidentified gray matter volume differences in patients with schizophrenia and their siblings with optimized voxel-based morphometry. METHODS: We studied 169 patients...

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Identifiers

PMID: 17689500
DOI: 10.1016/j.biopsych.2007.05.027
PMCID: PMC2390785

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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