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Article

The PAI-1 4G/5G gene polymorphism and ischemic stroke: an association study and meta-analysis.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jan 2000

Attia John, Thakkinstian Ammarin, Wang Yang, Lincz Lisa, Parsons Mark, Sturm Jonathan, McGettigan Patricia, Scott Rodney, Meldrum Cliff, Levi Christopher

Abstract excerpt

To investigate whether the 4G/5G polymorphism of plasminogen activator inhibitor type 1 (PAI-1) and the -7351 C/T polymorphism of tissue-type plasminogen activator (t-PA) are associated with ischemic stroke, we conducted a case-control study of 190 hospital cases of first-ever ischemic stroke and 185 community-based controls. Our findings do not indicate any association between the PAI-1 or t-PA polymorphisms and...

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Identifiers

PMID: 17689414
DOI: 10.1016/j.jstrokecerebrovasdis.2007.03.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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