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Article

Analysis of KLF transcription factor family gene variants in type 2 diabetes.

BMC medical genetics - 9 Aug 2007

Gutiérrez-Aguilar Ruth, Benmezroua Yamina, Vaillant Emmanuel, Balkau Beverley, Marre Michel, Charpentier Guillaume, Sladek Rob, Froguel Philippe, Neve Bernadette

Abstract excerpt

BACKGROUND: The Krüppel-like factor (KLF) family consists of transcription factors that can activate or repress different genes implicated in processes such as differentiation, development, and cell cycle progression. Moreover, several of these proteins have been implicated in glucose homeostasis, making them candidate genes for involvement in type 2 diabetes (T2D). METHODS: Variants of nine KLF genes were...

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Source

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Identifiers

PMID: 17688680
DOI: 10.1186/1471-2350-8-53
PMCID: PMC1994949

Genes

KLF2
KLF4
KLF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of KLF transcription factor family gene variants in type 2 diabetes.PMID 17688680Read ↗

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