Article
Genetic Variation in Kruppel like Factor 15 Is Associated with Left Ventricular Hypertrophy in Patients with Type 2 Diabetes: Discovery and Replication Cohorts.
EBioMedicine - 1 Apr 2017
Patel Sheila K, Wai Bryan, Lang Chim C, Levin Daniel, Palmer Colin N A, Parry Helen M, Velkoska Elena, Harrap Stephen B, Srivastava Piyush M, Burrell Louise M
Abstract excerpt
Left ventricular (LV) hypertrophy (LVH) is a heritable trait that is common in type 2 diabetes and is associated with the development of heart failure. The transcriptional factor Kruppel like factor 15 (KLF15) is expressed in the heart and acts as a repressor of cardiac hypertrophy in experimenta...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
