Article
Association analysis of Krüppel-like factor 11 variants with type 2 diabetes in Pima Indians.
The Journal of clinical endocrinology and metabolism - 1 Sept 2008
Ma Lijun, Hanson Robert L, Que Lorem N, Mack Janel L, Franks Paul W, Infante Aniello M, Kobes Sayuko, Bogardus Clifton, Baier Leslie J
Abstract excerpt
CONTEXT: Krüppel-like factor 11 (KLF11) is a transcription factor of the zinc finger domain family that has been shown to regulate expression of the insulin gene. An initial study reported that a KLF11 variant predicting a Q62R was associated with type 2 diabetes (T2D) in French Caucasians; however, subsequent studies have failed to identify an association between this variant and T2D in subjects from a similar...
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