Article
Autotomy behavior correlates with the DRG and spinal expression of sodium channels in inbred mouse strains.
Brain research - 18 Aug 2009
Persson Anna-Karin, Thun Jonas, Xu Xiao-Jun, Wiesenfeld-Hallin Zsuzsanna, Ström Mikael, Devor Marshall, Lidman Olle, Fried Kaj
Abstract excerpt
Patients who have suffered nerve injury show profound inter-individual variability in neuropathic pain even when the precipitating injury is nearly identical. Variability in pain behavior is also observed across inbred strains of mice where it has been attributed to genetic polymorphisms. Identification of cellular correlates of pain variability across strains can advance the understanding of underlying pain...
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