Article
Assessment of laboratory measurements and -308 TNFalpha gene promoter polymorphisms in normal bone mineral density.
Clinical rheumatology - 1 Mar 2008
Canhao Helena, Fonseca Joao Eurico, Caetano-Lopes Joana, Saldanha Carlota, Queiroz Mario Viana
Abstract excerpt
The aim of this study was to identify and evaluate laboratory parameters associated with normal bone mineral density (BMD) and to test if -308 tumour necrosis factor (TNF) alpha gene promoter polymorphisms could influence BMD. We performed a comparative cross-sectional study of four main groups: young healthy individuals (20-30 years); subjects aged 50 years or over with normal BMD; osteoporotic subjects aged 50...
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