Article
TNF-α and IL10 gene polymorphisms in women with postmenopausal osteoporosis.
European journal of obstetrics, gynecology, and reproductive biology - 1 Apr 2016
Kotrych Daniel, Dziedziejko Violetta, Safranow Krzysztof, Sroczynski Tomasz, Staniszewska Marzena, Juzyszyn Zygmunt, Pawlik Andrzej
Abstract excerpt
OBJECTIVE: Postmenopausal osteoporosis is a common disorder characterized by decreased bone mineral density (BMD). Proinflammatory cytokines are among the significant factors involved in bone turnover. They are the stimulants of bone resorption, acting directly on osteoclasts and osteoclast precursors. In this study, we examined the TNF-α (-308G>A) (rs1800629) and IL10 (-1082G>A) (rs1800896), (-592C>A)...
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