Article
Association of TNFSF11 gene promoter polymorphisms with bone mineral density in postmenopausal women.
Maturitas - 20 Oct 2006
Mencej Simona, Prezelj Janez, Kocijancic Andreja, Ostanek Barbara, Marc Janja
Abstract excerpt
OBJECTIVES: The receptor activator of nuclear factor-kappaB ligand (RANKL) is recognized as one of the important regulators of osteoclastogenesis. The expression of the tumour necrosis factor superfamily, member 11 (TNFSF11) gene, which encodes for RANKL protein, is increased relative to the expression of osteoprotegrin in cases of senile osteoporosis with hip bone fracture. Our aim was to find polymorphisms in...
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