Polymorphism rs2073618 of the TNFRSF11B (OPG) Gene and Bone Mineral Density in Mexican Women with Rheumatoid Arthritis.

doi:10.1155/2017/7680434

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Article

Polymorphism rs2073618 of the TNFRSF11B (OPG) Gene and Bone Mineral Density in Mexican Women with Rheumatoid Arthritis.

Journal of immunology research - 1 Jan 2017

Nava-Valdivia C A, Saldaña-Cruz A M, Corona-Sanchez E G, Murillo-Vazquez J D, Moran-Moguel M C, Salazar-Paramo M, Perez-Guerrero E E, Vazquez-Villegas M L, Bonilla-Lara D, Rocha-Muñoz A D, Martín-Marquez B T, Sandoval-Garcia F, Martínez-García E A, Fajardo-Robledo N S, Ponce-Guarneros J M, Ramirez-Villafaña M, Alcaraz-Lopez M F, Gonzalez-Lopez L, Gamez-Nava J I

Abstract excerpt

Osteoporosis (OP) is highly prevalent in rheumatoid arthritis (RA) and is influenced by genetic factors. Single-nucleotide polymorphism (SNP) rs2073618 in the TNFRSF11B osteoprotegerin (OPG) gene has been related to postmenopausal OP although, to date, no information has been described concerning whether this polymorphism is implied in abnormalities of bone mineral density (BMD) in RA. We evaluated, in a...

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PMID: 28758134
DOI: 10.1155/2017/7680434
PMCID: PMC5516719

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