Article
Bone mineral density of the lumbar spine is associated with TNF gene polymorphisms in early postmenopausal Japanese women.
Calcified tissue international - 1 Jun 2004
Furuta I, Kobayashi N, Fujino T, Kobamatsu Y, Shirogane T, Yaegashi M, Sakuragi N, Cho K, Yamada H, Okuyama K, Minakami H
Abstract excerpt
We investigated the relationships between tumor necrosis factor (TNF) gene polymorphism, circulating TNF-alpha (TNF-alpha) concentrations, and bone mineral density (BMD) in the lumbar spine. TNF gene polymorphisms studied were the Nco I polymorphism within the first intron of TNF-beta (TNF-beta) and three single nucleotide polymorphisms in the promoter region of the TNF-alpha gene, at positions -857, -863, and...
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