Article
ErbB3 mRNA expression correlated with specific clinicopathologic features of Japanese lung cancers.
The Journal of surgical research - 1 May 2008
Kawano Osamu, Sasaki Hidefumi, Endo Katsuhiko, Suzuki Eriko, Haneda Hiroshi, Yukiue Haruhiro, Kobayashi Yoshihiro, Yano Motoki, Fujii Yoshitaka
Abstract excerpt
BACKGROUND: ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of tyrosine kinase. A previous report has suggested that overexpression of ErbB3 protein was associated with lung cancer recurrence. Other reports suggested that high ErbB3 protein expression was associated with shorter survival in advanced non-small-cell lung carcinomas (NSCLC). The relationship between the erbB3 mRNA expression...
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