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Article

Association of the HTRA1 -625G>A promoter gene polymorphism with exudative age-related macular degeneration in a Central European population.

Molecular vision - 24 Jul 2007

Weger Martin, Renner Wilfried, Steinbrugger Iris, Köfer Katharina, Wedrich Andreas, Groselj-Strele Andrea, El-Shabrawi Yosuf, Schmut Otto, Haas Anton

Abstract excerpt

PURPOSE: Exudative age-related macular degeneration (AMD) is one of the most common causes of severe visual loss. Both environmental and genetic factors, such as the complement factor H (CFH) 402H allele, have been associated with AMD. Recently, the HTRA1 -625A allele was identified as a novel risk marker in both a North American and a Chinese population. The present study was performed to evaluate the...

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Source

Identifiers

PMID: 17679948

Genes

HTRA1
CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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