Article
Regulation of XSnail2 expression by Rho GTPases.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Sept 2007
Broders-Bondon Florence, Chesneau Albert, Romero-Oliva Francisco, Mazabraud André, Mayor Roberto, Thiery Jean Paul
Abstract excerpt
We analyzed the effects of Rho GTPases on XSnail2 expression during neural crest (NC) ontogeny in Xenopus laevis embryos. The ectopic expression of both dominant-negative (N-) and constitutively active (V-) Rho GTPase mutants after RNA or DNA microinjection disrupted the endogenous expression of XSnail2, XFoxD3, and XSnail1. V14RhoA and N17Rac1 were inhibitory, whereas N19RhoA and V12Rac1 increased NC marker gene...
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