Article
Small GTPase R-Ras participates in neural tube formation in zebrafish embryonic spinal cord.
Biochemical and biophysical research communications - 27 Jun 2018
Ohata Shinya, Uga Hideko, Okamoto Hitoshi, Katada Toshiaki
Abstract excerpt
Ras related (R-Ras), a small GTPase, is involved in the maintenance of apico-basal polarity in neuroepithelial cells of the zebrafish hindbrain, axonal collapse in cultured murine hippocampal neurons, and maturation of blood vessels in adult mice. However, the role of R-Ras in neural tube formation remains unknown. Using antisense morpholino oligonucleotides (AMOs), we found that in the spinal cord of zebrafish...
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