Article
Mef2c-F10N enhancer driven β-galactosidase (LacZ) and Cre recombinase mice facilitate analyses of gene function and lineage fate in neural crest cells.
Developmental biology - 1 Jun 2015
Aoto Kazushi, Sandell Lisa L, Butler Tjaden Naomi E, Yuen Kobe C, Watt Kristin E Noack, Black Brian L, Durnin Michael, Trainor Paul A
Abstract excerpt
Neural crest cells (NCC) comprise a multipotent, migratory stem cell and progenitor population that gives rise to numerous cell and tissue types within a developing embryo, including craniofacial bone and cartilage, neurons and glia of the peripheral nervous system, and melanocytes within the skin. Here we describe two novel stable transgenic mouse lines suitable for lineage tracing and analysis of gene function...
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