Article
Corticotropin releasing hormone (CRH) gene variation: comprehensive resequencing for variant and molecular haplotype discovery in monosomic hybrid cell lines.
DNA sequence : the journal of DNA sequencing and mapping - 1 Dec 2007
Shimmin Lawrence C, Natarajan Sivamani, Ibarguen Heladio, Montasser May, Kim Do-Kyun, Hanis Craig L, Boerwinkle Eric, Wadhwa Pathik D, Hixson James E
Abstract excerpt
Candidate gene association studies have met with mixed success due to many reasons including incomplete surveys of genetic variation and differences in patterns of genetic variation among study populations. We present the results of comprehensive variant discovery for the corticotropin releasing hormone gene (CRH on chromosome 8) encoding a neuropeptide that is central to many physiologic pathways. Mouse-human...
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