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Article

Phospholipase cbeta is critical for T cell chemotaxis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2007

Bach Tami L, Chen Qing-Min, Kerr Wesley T, Wang Yanfeng, Lian Lurong, Choi John K, Wu Dianqing, Kazanietz Marcelo G, Koretzky Gary A, Zigmond Sally, Abrams Charles S

Abstract excerpt

Chemokines acting through G protein-coupled receptors play an essential role in the immune response. PI3K and phospholipase C (PLC) are distinct signaling molecules that have been proposed in the regulation of chemokine-mediated cell migration. Studies with knockout mice have demonstrated a criti...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemokine CXCL12

Share to GTP-Binding Protein alpha Subunits, Gi-Go

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Share to Type C Phospholipases

Source

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Identifiers

PMID: 17675482
DOI: 10.4049/jimmunol.179.4.2223
PMCID: PMC3228861

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17675482-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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