Article
Mapping and Characterization of the Primary and Anamnestic H-2 <sup>d</sup> -Restricted Cytotoxic T-Lymphocyte Response in Mice against Human Metapneumovirus
2 Aug 2007
Abstract excerpt
Cytotoxic T lymphocytes (CTLs) are important for the control of virus replication during respiratory infections. For human metapneumovirus (hMPV), an H-2(d)-restricted CTL epitope in the M2-2 protein has been described. In this study, we screened the hMPV F, G, N, M, M2-1, and M2-2 proteins using three independent algorithms to predict H-2(d) CTL epitopes in BALB/c mice. A dominant epitope (GYIDDNQSI) in...
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