Immunization of mice with vaccinia virus-M2 recombinant induces epitope-specific and cross-reactive Kd-restricted CD8+ cytotoxic T cells.

doi:10.1128/JVI.67.7.4086-4092.1993

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Article

Immunization of mice with vaccinia virus-M2 recombinant induces epitope-specific and cross-reactive Kd-restricted CD8+ cytotoxic T cells.

Journal of virology - 1 Jul 1993

Kulkarni A B, Morse H C, Bennink J R, Yewdell J W, Murphy B R

Abstract excerpt

The M2 protein of respiratory syncytial virus (RSV) is a protective antigen in H-2d, but not H-2b or H-2k mice. None of the other RSV proteins, excluding the surface glycoproteins that induce neutralizing antibodies, is protective in mice bearing these haplotypes. Thus, the M2 protein stands alone as a nonglycoprotein-protective antigen of RSV. The M2 protein is a target for murine Kd-restricted cytotoxic T...

Topics

Alleles
Amino Acid Sequence
Animals
Cross Reactions
Cytotoxicity, Immunologic
Epitopes
Female
Genetic Vectors
H-2 Antigens
HN Protein
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred BALB C

Molecular Sequence Data

Oligopeptides

Respiratory Syncytial Viruses

T-Lymphocytes, Cytotoxic

Vaccines, Synthetic

Vaccinia virus

Source

Open in PubMed Open full text

Identifiers

PMID: 7685408
DOI: 10.1128/JVI.67.7.4086-4092.1993
PMCID: PMC237777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7685408-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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