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Article

Matrix Protein 2 Vaccination and Protection against Influenza Viruses, Including Subtype H5N1

1 Mar 2007

Abstract excerpt

Changes in influenza viruses require regular reformulation of strain-specific influenza vaccines. Vaccines based on conserved antigens provide broader protection. Influenza matrix protein 2 (M2) is highly conserved across influenza A subtypes. To evaluate its efficacy as a vaccine candidate, we vaccinated mice with M2 peptide of a widely shared consensus sequence. This vaccination induced antibodies that...

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Identifiers

PMID: 17552096
DOI: 10.3201/eid1303.061125

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