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Article

Direct binding and activation of protein kinase C isoforms by aldosterone and 17beta-estradiol.

Molecular endocrinology (Baltimore, Md.) - 1 Nov 2007

Alzamora Rodrigo, Brown Laura R, Harvey Brian J

Abstract excerpt

Protein kinase C (PKC) is a signal transduction protein that has been proposed to mediate rapid responses to steroid hormones. Previously, we have shown aldosterone directly activates PKCalpha whereas 17beta-estradiol activates PKCalpha and PKCdelta; however, neither the binding to PKCs nor the mechanism of action has been established. To determine the domains of PKCalpha and PKCdelta involved in binding of...

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Source

Identifiers

PMID: 17666590
DOI: 10.1210/me.2006-0559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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