Article
pp90RSK- and protein kinase C-dependent pathway regulates p42/44MAPK-induced LDL receptor transcription in HepG2 cells.
Journal of lipid research - 1 Mar 2003
Kapoor Gurpreet S, Golden Carmen, Atkins Brett, Mehta Kamal D
Abstract excerpt
We have previously shown that different extracellular stimuli require signaling through the Raf/MEK/p42/44MAPK cascade to induce LDL receptor expression. The present studies were designed to delineate the molecular mechanisms underlying p42/44MAPK-induced LDL receptor transcription in HepG2-Delta...
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